CALI Calculator

Comorbidity–Advanced Lung Cancer Inflammation Index risk-score calculator for older patients with advanced NSCLC receiving first-line immunotherapy.

Updated final model: OS λ = 0.5; PFS λ = 1.0; development cohort n = 115.

Patient and Laboratory Inputs

Height (cm)

Weight (kg)

Albumin (g/L)

Neutrophil count (10⁹/L)

Lymphocyte count (10⁹/L)

Hypertension

Diabetes mellitus

COPD

Weight loss ≥5% within 3 months

Results

Derived Values

BMI—

NLR—

ALI—

CALI-OS Risk

Risk score—

Linear predictor—

Risk-score cutoff0.950624

Risk group—

CALI-PFS Risk

Risk score—

Linear predictor—

Risk-score cutoff0.980752

Risk group—

Risk groups are assigned using the fixed development-cohort median risk-score cutoffs: OS = 0.9506238054 and PFS = 0.9807522447.

Calculation Notes

BMI = weight / (height/100)^2; NLR = neutrophil / lymphocyte; ALI = BMI × albumin / NLR.

Linear predictor = Σ β × ((patient value − development-cohort mean) / SD). Risk score = exp(linear predictor). OS and PFS use endpoint-specific β coefficients and fixed development-cohort standardization parameters.

This calculator is intended for prognostic stratification only and should not replace clinical judgment. All calculations are performed locally in the browser; no patient data are uploaded or stored.